Breast cancer metastasis whole body bone scan


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Whole-body bone SPECT in breast cancer patients: the future bone scan protocol?




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Take your medicines as normal Brast your doctor tells you otherwise. Phone the department where you are having the scan if you are pregnant or breastfeeding. You might have to stop breastfeeding for a short period of time after having the scan. So you might want to store enough expressed milk for 1 or 2 feeds beforehand. The staff at the department will advise you.

Bone scan Breast body metastasis cancer whole

You have to arrive at the hospital about 4 hours before your scan. Your appointment letter will tell you the exact time. What happens First, a technician gives you an injection of a radioactive liquid called a radionucleotide. They inject it through a small tube into your bloodstream. The injection might make you feel hot and flushed for a minute or two but this is normal. You might have a quick test scan immediately after the injection.

You wait for about 4 hours while the cancr liquid travels through the blood and collects in your bones. It tends to collect more in areas where the bone is breaking down and repairing itself. They look darker than other areas of bone. Waiting for the scan Your radiographer will ask you to drink plenty of shole while you wait for your scan. This flushes the radionucleotide round your system well. Discussion There are many reports demonstrating mimicking bony lesions on metastazis scan in patients with infectious and inflammatory diseases, and cancers including breast cancer [ 6 - 9 ].

But no reports demonstrate mimicking osseous metastasis in ribs on bone scan in patients with breast cancer. Early stage of breast carcinoma is usually determined by mammogramfollowed by biopsy and pathological diagnosis. Bone scan is the standard method to assess for metastatic lesions associated with breast cancers. These cancers have higher incidence of osteoblastic than osteolytic lesions. Suspicious bone metastasis which has high incidence in patients with stage III and IV breast cancer is normally monitored by bone scan.

Bone scan is used less frequently in patients with stage I and II breast cancer, given the occurrence of osseous metastasis at early stages is rare [ 23 ]. Bone scan is non-specific but highly sensitive in diagnosing osseous metastasis. Bone scan shows more sensitivity than plain film, an advantage for whole body imaging. However, bone scan lacks specificity and mainly detects osteoblastic lesions. False positive findings can result from calcification of soft tissue of primary and metastatic malignancy, benign bone neoplasms, bone fracture, healing trauma, and osteomyelitis.

The current case demonstrates multiple abnormal uptakes in the ribs of a patient with metastatic breast cancer. This mimicking rib metastasis from metastatic pulmonary nodules most likely resulted from microcalcification of the malignant tissues.

This is the first time that metastatic pulmonary nodules mimicking rib metastatic lesions has been reported in the literature, although metastatic breast cancer demonstrates osseous lesions in a xancer range of axial and appendicular skeleton, such as in spine [ 11 ], ribs [ 12 ], pelvic bone [ 13 ], femur bkdy 14 ], skull [ 1516 ], and sternum [ 17 ]. An accurate diagnosis enables appropriate therapy and management. Abnormal findings on body scan in patients with breast cancer or other cancers may represent infectious and inflammatory diseases, extra-skeletal muscular ossification and benign osseous tumor [ 1 - 51819 ]. This review did not consider studies of imaging in monitoring response to therapy.

Data extraction included information on study characteristics and quality appraisal, as well as quantitative data on test accuracy. Eligible studies were reviewed by both authors and disagreement on extracted information was resolved by discussion and consensus. Items included in the quality appraisal and evidence tables were adapted from recommendations for design of studies of comparative test accuracy [ 15—18 ] including checklists used in appraisal of imaging studies, and international standards for reporting of studies of test accuracy [ 19 ]. Study-specific estimates of sensitivity and specificity were extracted or were calculated.

The local diagnosis of CT-negative supplements was made as beaches: Hence, the time of osteolytic, osteoblastic, or collected BM may have not depending on the fullness quota used, private to interracial porn capability for sexual imaging tests [ 1 ].

Where a sufficient number of studies reported comparisons of the same scaj tests, descriptive analysis median and range was performed. Canncer Eighty-eight patients with bone metastases from breast cancer were eligible for this study. Histological confirmation of bone metastases was obtained in 31 patients. The bone metastases were visually classified into four types based on their metastasi tomograp